Research on Embryonic Safety Issues

The Challenges of Embryonic Stem Cells

Scientists are working non-stop to overcome the challenges of mouse feeder cell contamination, genetic instability and tumor development that have been safety concerns with embryonic stem cells.

• In Vitro culture can reduce embryonic totipotency

• TEM to evaluate abnormalities in embryonic cell structure

• Reducing tumor formation with adhesion molecule antibodies

• Embryonic stem cell transplants into mouse models can result in malignant tumors

• Animal models for testing tumorigenesis in transplants

• Differentiated cells from embryonic stem cells may require immunosuppressants

• Embryonic stem cells could be used for diabetes if the risk of tumors were reduced

• Embryonic stem cell derived liver cells can still contain undifferentiated cells that can cause tumor formation