Stem Cell Treatments to Improve symptoms in Down Syndrome
The clinical characteristics of Down syndrome, caused by the triplication of the fragment 21q22 of chromosome 21 (trisomy 21) include mental retardation, craniofacial abnormalities, clinical defects of the heart, gut and immune system, and an increased risk of other diseases, including leukemia and Alzheimer's disease. Down syndrome is further complicated by the accumulation of toxic amyloid beta deposits in the brain and perhaps blood vessels.
A comprehensive medical program that includes
1) Eliminating infections
2) Eliminating metal toxicity
3) Providing mitochondrial support (to produce ATP energy for the cell)
4) Providing antioxidants (to reduce amyloid beta and for neuroprotection)
5) Providing growth factors for neuroprotection and neurogenesis
6) Providing umbilical cord stem cells (especially cells transfected with needed genes)
holds promise for reducing some of the symptoms of Down syndrome. This is a new frontier for human umbilical cord stem cells and one that is very exciting. We are optimistic because some of the children with cerebral palsy have responded to cord stem cells with cognitive improvements, including improvements in comprehension, logic, increased vocabulary, learning and memory.
If you would like to donate to research involving animal models of Down syndrome treated with cord stem cells and cord stem cells transfected with various genes, please click here. For research on Down syndrome, click here.
This information is presented for educational purposes only.